Eruptive Keratoacanthomas Associated With Leflunomide.

Eruptive Keratoacanthomas AssociatedWith Leflunomide The keratoacanthoma (KA) is a rapidly growing, welldifferentiated epidermal neoplasm that may be locally invasive or may spontaneously resolve. Most often, KA presents as a solitary lesion; however,multipleKAs canbe seen in various syndromes, including Muir-Torre syndrome, the autosomal dominant Ferguson-Smith syndrome, and Grzybowskitype eruptive KAs.1 Severalmedicationshavebeen temporally associatedwith eruptive KAs. Recently in the literature there has been a report of eruptive KAs following treatment with leflunomide.2 The KAs resolved after stopping treatment with the medication. Herein, we report another case of multiple KAs in a patient undergoing treatment with leflunomide.